Ana Dfs
The most characteristic ANA specificity associated with DFS pattern is the anti-DFS70 antibody (synonym LEDGF antibody).
Ana dfs. The DFS pattern on HEp-2 cells is well differentiated from the classic "homogeneous" ANA pattern associated with dsDNA antibodies. Anti-dense fine speckles 70 (anti-DFS70) antibodies are a type of non-disease specific ANA that may be found in healthy individuals and account for half of the ANA positivity in the healthy population. ANA DUTY FREE SHOP.
The dense fine speckled (DFS) nuclear pattern is one of the most common IFA patterns encountered in the ANA screening routine of clinical diagnostic laboratories, often occurring in very high titers. First described more than 50 years ago, ANAs remain the most sensitive serologic mark-er for evaluating patients with suspected connective tissue diseases (CTDs), also referred to as ANA-associated rheumatic diseases (AARDs) (1). Additionally, they may be found in a wide spectrum of non-autoimmune diseases such as atopic dermatitis, malignancies, eye disorders and others.
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